If you have a car with good MPG then maybe.
I'll make £80 this weekend, but most of the money is coming from mileage. That pays for fuel and then some because my car is fuel effective. So for March, 5 weekends and that would be £400, minus £50 to fill the car up eventually and that's £350 for the month.
However, that needs me to be booked Saturday and Sunday. It also needs me to booked some distance away. I wouldn't rely on it as a sole income, it's a nice bit of extra change I suppose, but not much more than that.
For one thing, you're at the mercy of the weather!
But even in an ideal world, assuming you did a youth match in the morning, adults match (or two adult matches on the afternoon/evening slot), then Sunday League/Dev/Ladies league... Your legs probably wouldn't forgive you if you did that regularly and you'd be so mentally exhausted I don't think you'd referee very well.